Endoüroloji Bülteni

Yazarlar: Ali Erhan EREN, Selm TAŞ

Konular:Üroloji ve Nefroloji

Anahtar Kelimeler:Bladder cancer,Genetic background,Young patıents

Özet: Although bladder cancer can be seen at any age, it is rarely seen in young patients. Patients often present with the complaint of painless clotted hematuria. Although there is no exact age range for young patients in the literature, published papers have defined classifications as under 20 years old, between 20 and 40 years old and over 40 years old. The PI3K pathway and the associated PIK3CA gene are located on chromosome 9 (1). In this case report, we aimed to present a young patient with PIK3CA gene mutation that has unclear effects on bladder cancer. A 22-year-old male patient applied to center. Ultrasonography showed a 6x4 cm papillary mass near the base of the left lateral wall of the bladder. Subsequently, transurethral resection was performed. Histopathological examination established the diagnosis of superficial low-grade papillary urothelial carcinoma (pTa Low-Grade) based on the WHO/ISUP 2004 classification. It was concluded that the PIK3CA gene mutation in this case may be related to bladder cancer.

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