Journal of Health Sciences and Medicine

Yazarlar: ["Esin Merve EROL KOÇ", "Selen YAMAN", "Yasemin TAŞÇI", "Nihal ÖMÜR", "Fatma Meriç YILMAZ", "Jale KARAKAYA", "Rahime BEDİR FINDIK"]

Konular:-

DOI:10.32322/jhsm.1075563

Anahtar Kelimeler:Placental calcification,Term pregnancy,Calcium,Fetuin A

Özet: Aim: Fetuin A is a multifunctional protein which is a marker of pathological calcification in several diseases. This study aimed to evaluate serum fetuin A level in term pregnancies with grade 3 placental calcification. Material and Method: Fifty-seven pregnant women who applied obstetrics outpatient clinic for routine pregnancy follow-up at term were included in this study. The study was designed prospectively. Patients with grade 3 placental calcification (n=29) were compared to patients with non-calcified placenta (n=28) in terms of serum fetuin A levels. Results: Maternal serum calcium levels of pregnant women with grade 3 calcified was significantly increased compared to pregnant women with non-calcified placenta. There was no significant difference between the fetuin A levels of study and control groups. The fetuin A level was not found to be correlated with maternal serum calcium level. Conclusion: Fetuin A has been targeted as a marker for pathological calcification. The findings of the current study may support the thought that term placental calcification may be physiological rather than a pathological process.

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