Journal of Health Sciences and Medicine
Yazarlar: Derya YENİBERTİZ, Berna AKINCI ÖZYÜREK, Sertaç BÜYÜKYAYLACI ÖZDEN, Aslıhan GÜRÜN KAYA, Yurdanur ERDOĞAN
Konular:Sağlık Bilimleri ve Hizmetleri
DOI:10.32322/jhsm.738446
Anahtar Kelimeler:Idiopathic pulmonary fibrosis,IPF,GAP stage,CRP/Albumin ratio (CAR)
Özet: Aim: We aimed to compare the gender, age, and physiology index and C-reactive protein/albumin ratio in order to evaluate the prognosis, clinical course and survival of patients with idiopathic pulmonary fibrosis. Material and Method: Forty-seven patients with idiopathic pulmonary fibrosis diagnosed by radiologically or pathologically in the 8th clinic of our hospital between January 2013 and December 2018 included to the study. Demographic characteristics, pulmonary function tests, 6-minute walk test values, echocardiography results, life span, additional diseases, treatment information, laboratory results of patients, gender, age and physiology indexes and initial C-reactive protein/albumin ratio of the patients were recorded from the patient files. Results: According to gender, age and physiology index there were 25 (53.2%) patients in stage I, 11 (23.4%) patients in stage II, and 11 (23.4%) patients in stage III. The patients were divided into 2 groups according to their life conditions. The rate of respiratory failure, the mean pulmonary arterial pressure and gender, age, and physiology stage were significantly higher (p grup 0.05) in the exitus group. The 6- minute walk test was significantly lower in the exitus group (p<0.05). C-reactive protein/albumin ratio results were similar in both groups and there were no significant differences according to other parameters in both groups too. There was no significant difference between the C-reactive protein/albumin ratio values of the patients in each of the three gender, age, and physiology stages. Conclusion: Gender, age, and physiology stage is easy and useful but C-reactive protein/albumin ratio isn’t convenient to predict the prognosis of idiopathic pulmonary fibrosis. The elevation of pulmonary arterial pressure, low 6 minute walk test and presence of respiratory failure are poor prognostic factors in idiopathic pulmonary fibrosis.