Turkish Journal of Veterinary and Animal Sciences

Yazarlar: Junfang JIANG, Yongqing JIANG, Zhigang ZHU, Zirong XU

Konular:-

Anahtar Kelimeler:Key words: PPARg,Gene expression,Fat deposition,Pigs

Özet: PPARg is a member of the peroxisome proliferator-activated receptor subfamily of nuclear hormone receptors. PPARg has been showed to be a key regulator of adipocyte differentiation and lipid metabolism. The pattern of PPARg gene expression in different growth stages and its relation with adipose deposition in pigs is studied. Fifteen female Duroc×Landrace×Yorkshire pigs in 5 groups with 3 pigs in each grup, at live weight of 1, 30, 50, 70, and 90 kg were used to study the developmental gene expression of PPARg in subcutaneous adipose tissue by means of semi-quantitative RT-PCR. The results showed the PPARg mRNA levels of porcine adipose tissue increased as pigs grew and deposited fat from 1 to 90 kg live weight (P < 0.05). The present data indicated a close positive correlation between the levels of PPARg gene expression and the fat deposition rate in pigs. The experiment showed the total adipose weight increased significantly with body weight (P < 0.05).

---