Anatolian Journal of Emergency Medicine
Yazarlar: Arzu DENİZBAŞI ALTINOK, Çiğdem ÖZPOLAT, Özge ONUR
Konular:-
Anahtar Kelimeler:Opioid Antagonist,Naloxone,Resuscitation
Özet: Opioid antagonists are a unique class of drugs in terms of not only chemical and pharmacological properties but also efficiency in clinical practice. This class, namely Naloxone, is used widely to revert opioid induced respiratory depression in cardiopulmonary arrest cases. In evidence based medicine Naloxone administration is an important management. As a result of clinical effectiveness and popularity, different drug formulations of Naloxone have been developed and different Naloxone administrations have been studied. Naloxone is a drug that can be administered via intramuscular, intranasal, subcutaneous, inhalation or endotracheal routes. Appropriate dosing and concentration vary according to the route of administration. This review is written to summarize the use of opioid antagonists in in or out of hospital settings with recent indications.