Eurasian Journal of Biological and Chemical Sciences

Yazarlar: Rahmi CANBAR, Enver YAZAR YAZAR

Konular:Veteriner Hekimlik

DOI:10.46239/ejbcs.782004

Anahtar Kelimeler:Tilmicosin,Cardiotoxicity,Toxicity

Özet: Tilmicosin is a macrolide group antibiotic developed only for veterinary medicine. The use of the product is approved in cattle, sheep, pigs, turkeys and chickens. It shows bacteriostatic effect by inhibiting protein synthesis in microorganisms. They are especially used in the treatment of respiratory system infections in these animals. Cardiotoxicity, which is defined among the side effects of macrolide group antibiotics, is quite prominent in tilmicosin. It can cause cardiotoxicity and death, when non-subcutaneous applications in recommended animals or extra-label use. Humans can often be accidentally exposed to tilmikosin, and deaths can be observed. Tilmicosin is one of the most reported side effects among veterinary drugs. In this review, it could be tried to give information about the toxicity, mechanism and treatment options of tilmicosin in humans and animals.

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