Eurasian Journal of Biological and Chemical Sciences

Yazarlar: Faiza SHAFİ, Muhammad AJAİB, Khizar Hayat BHATTİ, Muhammad Faheem SİDDİQUİ, Afsheen KHAN

Konular:Temel Bilimler

DOI:10.46239/ejbcs.863842

Anahtar Kelimeler:Phytochemicals,Anthelmic activity,Medicinal plants

Özet: In present study the ethanolic extracts of leaf and seed of Cassia occidentalis were investigated for their phytochemical properties and anthelmintic activity against Haemonchus controtus at different concentrations (100, 150, 200 mg/ml). Alkaloids, flavonoids, saponins, tannins, phenols, steroids and carbohydrates are present in both leaf and seeds crude extracts. The study is mainly concerned with the determination of time of paralysis and time of death of the worms. When there was a gradual increase in the dose, a gradual increase in the anthelmintic activity was observed. The least time for the death and paralysis was recorded at concentration of 50mg/mL and maximum time for death and paralysis was recorded at 10mg/mL concentration. The ethanolic extract of the leaf and seed showed a significant anthelmintic activity at highest concentration of 50 mg/ml. So the C. occidentalis plant can be used as anthelmintic drug for the treatment of gastrointestinal helminthic infections after clinical trials, toxicological effects and isolation of chemical compounds.

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