Veteriner Farmakoloji ve Toksikoloji Derneği Bülteni
Yazarlar: Sultan Nurhan AYIKOL, Furkan KUTLU, Onur Mücahit DİNCER, Farah Gonul AYDIN
Konular:Veteriner Hekimlik
DOI:10.38137/vetfarmatoksbulten.834364
Anahtar Kelimeler:Aquaculture,Antibiotic,Biofilm,Resistance
Özet: Aquaculture industry is a rising industry, fills important amounts of animal protein production. However, climate change, ecological disruption, population increase and especially diseases are affecting the national economy on a macro scale. Most commonly encountered disease agents are: Aeromonas spp., Vibrio spp. There are many methods to control and treat for aquatic diseases in the World and Turkey. While vaccination programs are used regularly, in case it can’t be applied appropriately or not at all, antibiotics still plays an important role in treatment. In Turkey, antibiotics are licenced for finfish: 15 of florfenicol, 12 oxytetracycline, 9 sulfadiazine + trimethoprim, 2 enrofloxacin and 2 amoxicillin. Due to usage of those antibiotics with the wrong dosage, time of use, without an antibiogram test and usage of the wrong combination of drugs leads to bacterial antimicrobial resistance and the insufficient number of effective drugs to be used. While considering this situation on a national and international scale; with increased antimicrobial resistance, effects of antibiotics are reduced, increase of mortality and cost of treatment creates increasing global problems not just animal but also human health. Use of antibiotics as oral and premixes, increases residues in various places, making it easier to reach the aquatic environment and other animals thus increasing antimicrobial resistance even further. Minimum inhibitor concentration (MIC) of antibiotics used against planktonic bacteria does not match the value to prevent, inhibit, reduce or eradicate biofilm produced by them In this review, role of biofilm bacteria in increased antimicrobial resistance and mechanisms affecting that are evaluated considering growing aquaculture industry, especially in Turkey.