Spor Eğitim Dergisi

Yazarlar: Orkun AKKOÇ, Ayşegül BİRLİK, Canan SERCAN DOĞAN, Özlem KIRANDI, Korkut ULUCAN

Konular:-

Anahtar Kelimeler:İronman Triathlon,IL-6,HIF1A,MCT1,PPAR-a

Özet: The aim of this study was to determine the IL-6 (rs1800795), HIF1A (rs11549465), MCT1 (rs1049434), PPAR-a (rs4253778) genotype distributions and allele frequencies of Turkish Iroman triathlon athletes. Ten elite male İronman triathlon athletes participated in the study. DNA samples of the subjects were obtained from venous blood. Genotyping of samples was performed by Real-Time PCR. The statistics of the study were tested in SPSS 21 program. Genotype and allele frequence differences were compared by using Chi square test and p <0.05 was accepted as significant. Genotype distribution of PPAR-A gene; GG 9, GC 1 and CC 0 (p=, 011). When allele distribution of PPAR-A gene was examined, G allele frequency was found to be higher than C allele frequency (p=, 000). When the genotype and allele frequency distribution of MCT1 gene were examined, AA 9, AT 1 and TT 0 were found and A genotype showed high distribution (p=, 011). On the other hand, the A allele distribution was higher than the T allele (p=, 000). Genotype distribution of HIF1A1 gene was found to be CC 7, CT 1, TT 0 (p=, 034). G allele frequency of HIF1A1 gene was higher than C allele frequency (p=, 000). In the IL 6 gene, GG 6, GC 1 CC 0 were found and GG genotype was found high in the genotype distributions (p=, 044). G allele showed high distribution in allele frequency distribution of IL 6 gene (p=, 012). İn conclusion, Athletic performance was associated with PPAR-A, MCT1, HIF1A1 and IL 6 genesin Turkish İronman athletes .

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