Turkish Journal of Internal Medicine

Yazarlar: Mehmet SEZEN, Abdülmecit YILDIZ, Kamil DİLEK, Mustafa GÜLLÜLÜ, Mahmut YAVUZ, Ayşegül ORUÇ, Mehmet Fethullah AYDIN, Alparslan ERSOY

Konular:Genel ve Dahili Tıp

DOI:10.46310/tjim.876204

Anahtar Kelimeler:Sjogren syndrome,Focal segmental glomerulosclerosis,Nephrotic syndrome

Özet: Sjogren's syndrome (SjS) is a chronic, slow-progressing, autoimmune and lymphoproliferative disease. The main symptoms of the syndrome are xerostomia and keratoconjuctivitis sicca as a result of chronic inflammatory infiltration of the salivary and lacrimal glands. Focal Segmental Glomerulosclerosis complicating primary Sjögren's syndrome is extremely rare. We report on a 39-year-old woman with 5 years history of sjogren syndrome who was found to have nephrotic syndrome. Histopathological findings in kidney biopsy compatible with focal segmental glomerulosclerosis. Steroid therapy was initiated (oral prednisolone at a dose of 15 mg/day) and Cyclosporine 2 * 100mg/d. FSGS, which is associated with sjögren's syndrome, was considered suitable for the presentation because of its rare occurrence

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