Turkish Journal of Internal Medicine

Yazarlar: Neslihan Hazel SAYDAM, İbrahim Ethem PINAR, Tuba ERSAL, Cumali YALÇIN, Bedrettin ORHAN, Ömer CANDAR, Vildan OZKOCAMAN, Fahir ÖZKALEMKAŞ

Konular:Genel ve Dahili Tıp

DOI:10.46310/tjim.876554

Anahtar Kelimeler:Blastic plasmacytoid dendritic cell neoplasia,Cutaneous lymphoma,NK-cell lymphoma

Özet: Blastic Plasmacytoid Dendritic Cell Neoplasia (BPDCN) is a rare hematological malignancy whose pathogenesis has not yet been elucidated. Skin, bone marrow, and lymph node involvement can be observed, and it is generally seen in men and old adults. Immunohistochemistry (IHC) features of skin and bone marrow biopsy are essential for diagnosis. There are no standardized treatment options for this malignancy, and the prognosis is particularly poor. Although there are no standardized treatment options for this malignancy, multiple agent chemotherapies such as Hyper-CVAD and CHOP can be used. Bone marrow transplantation may be an option for patients with life expectancy. More case reports are required to understand and manage this extremely rare malignancy. We report the case we encountered in our clinic and selected CVP as the treatment approach.

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