Turkish Journal of Internal Medicine

Yazarlar: Mehmet USTA, Alparslan ERSOY, Yavuz AYAR

Konular:-

Anahtar Kelimeler:Azathioprine,Mycophenolate mofetil,Kidney transplantation recipient

Özet: Abstract Aim: This study investigated the effect of mycophenolate mofetil (MPA) treatment instead of azathioprine (AZA) on renal function after kidney transplantation.  Methods: Thirteen of all recipients were taking a cyclosporine-based regimen and serum creatinine levels were above 1.5 mg/dL. In 13 patients, MPA treatment was started instead of AZA. Renal functions were evaluated for 12 months after MPA treatment.  Results: Serum creatinine levels increased from 2.11±0.48 mg/dL to 2.16±0.72 mg/dL at 12th months. This increase was not statistically significant. Serum creatinine levels decreased in 5 of 13 patients.  Conclusion: In selected patients, conversion from AZA to MPA may slow down the rate of deterioration in graft functions.

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