Turkish Journal of Internal Medicine

Yazarlar: Canan ERSOY, Alparslan ERSOY

Konular:-

Anahtar Kelimeler:Obesity,Overweight,Hypertension,Kidney

Özet: Obesity is an important public health problem with increasing frequency, leading to different comorbidities including hypertension and can cause mortality. Possible mechanisms that increase blood pressure in overweight and obese people are renal damage, activation of the renin-angiotensin-aldosterone system, insulin resistance, hyperinsulinemia, sleep apnea syndrome, leptin-melanocortin pathway and genetic predisposition. Most of these mechanisms stimulate the sympathetic nervous system. Medical nutrition therapy, lifestyle interventions, medical and/or surgical antiobesity treatment modalities contribute to the control of blood pressure via weight loss. Besides antihypertensive medications should be chosen carefully in overweight and obese patients and drug groups preventing weight loss should not be preferred if possible. 

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