Turkish Journal of Health Science and Life

Yazarlar: Mesut GÖÇER

Konular:Sağlık Bilimleri ve Hizmetleri

Anahtar Kelimeler:SjögrSyndrome,Demographic,Clinical Features,Retrospective

Özet: Abstract Background: Sjögren’s syndrome (SS) is an autoimmune disease with a broad range of systemic manifestations. This study was conducted to determine demographic and clinical features of primary SS patients.   Methods: In this study were included the patients with primary SS (pSS) diagnosed between 2004-2014 years at the Akdeniz University Hospital, Antalya, Turkey. The clinical and laboratory features were retrospectively obtained from medical charts.   Results: We had 718 patients with suspected pSS at 10 years. 372 patients were classified as pSS according to 2012 American Collage of Rheumatology Classification Criteria for Sjögren’s Syndrome. pSS was more frequent among women and ratio women/men was 11/1. The mean age at the time of pSS diagnosis was 50.3±11.81 years. In men, pSS was diagnosed at an older age, and lung involvement was common than women. Joint involvement is the most common extraglandular involvement. Anemia is present in 21.1 % of the patients. Malignancy was diagnosed in 14 patients (3.8%) and 18 patients died (4.8%) during follow-up. Hydroxychloroquine is the most preferred drug as a therapeutic agent   Conclusions: Features of primary SS obtained in this study are similar to those found in some national and international studies, but we observed lung involvement higher male than female.

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