Eurasian Journal of Toxicology
Yazarlar: Hacer Efnan MELEK ARSOY, Fatih GÜNEYSU
Konular:Toksikoloji
DOI:10.51262/ejtox.873819
Anahtar Kelimeler:Poisoning,Pediatric emergency,Inflammatory,NLR
Özet: Objective: To keep up-to-date and enlighten the demographic characteristics of children admitted to the emergency department with poisoning and the treatment strategies of physicians, to examine laboratory parameters, and to ensure rapid and effective interventions. Materials and Methods: Patients aged 0-18 years who were admitted to the Sakarya Training and Research Hospital Pediatric Emergency Service for 24 months in 2018-2020 for accidental or suicidal poisoning were included in our study. Age, gender, location of the cases at the time of poisoning, first intervention by the family, if any, how long after the poisoning, the substance causing the poisoning, the route of poisoning, the accidental / deliberate exposure, the use of antidote or active charcoal condition, need for hospitalization or intensive care, duration of hospital stay, presence of mortality and morbidity, and some laboratory data were recorded. The relationship between inflammatory parameters and variables was also investigated. Results: It was determined that 74 girls (23.0%) and 5 boys (1.7%) committed suicide, 235 girls (74.6%) and 266 boys (90.6%) were accidentally poisoned. A statistically significant relationship was found between the purpose of poisoning and hospitalization day classes (χ2 = 13.776; p = 0.008). A weakly significant correlation was found between AST, ALT, WBC, lymphocyte, platelet, CRP, INR values, the AST and INR values were higher in mouse poisoning but not statistically significant (p> 0.05), WBC value in poisoning with cleaning materials It was found that it was significantly high (p <0.05), and it was significant in caustic corrosive substance intoxications (p <0.05). The CRP value is not significantly different (p> 0.05). Neutrophil / lymphocyte ratio (NLR) increases with age (p <0.05) and increases significantly in patients who come to the hospital late (p <0.05). Conclusion: As first intervention is very important in patients who come to the emergency, it is very important to seek consultation from other branches such as pediatric surgery and child psychiatry. Blood tests performed from patients who come to the emergency room can give information about the status of poisoning and prognosis. Troponin I level can be supportive in terms of treatment plan in carbon monoxide poisoning. In particular, inflammatory parameters and neutrophil / lymphocyte ratio are among the parameters that must be evaluated.