Eurasian Journal of Toxicology

Yazarlar: Ömer Faruk GEMİŞ, Abdullah Osman KOÇAK

Konular:Acil Tıp

Anahtar Kelimeler:Acetaminophen,Intoxication,Paracetamol intoxication,INR,Liver function tests

Özet: Objective: This study was planned to analyze some variables such as demographic, clinical, treatment, side effects, laboratory data of patients taking paracetamol for self-harm in a tertiary emergency department. Materials and Methods: This is a retrospective study. Patients over 18 years of age who received paracetamol active substance for suicidal purposes in the emergency department of Atatürk University Research Hospital between 14.01.2012 and 04.05.2019 were included in the study. Patients with chronic disease, pregnant women, patients with poor general condition and missing data were excluded from the study. Results: 129 patients were included in the study. 89 (69%) of the patients were female. The mean age of the patients was 25.8 ± 8.6 years. The ages of the patients ranged from 18 to 69 years. Forty-three patients had received paracetamol in toxic doses. There was a correlation between the amount of paracetamol and blood paracetamol levels. There was no significant relationship between the amount of paracetamol and other blood parameters. Conclusion: In our study, there was a correlation between the amount of paracetamol taken and blood paracetamol level. However, there was no statistically significant difference in liver function tests and International Normalized Ratio (INR) values. Further prospective studies are needed.

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