Asian Pacific Journal of Health Sciences

Yazarlar: Santosh Kumar Verma, Priyanka Bhardwaj, Sangeeta Rani

Konular:-

DOI:10.21276/apjhs.2018.5.1.30

Anahtar Kelimeler:Cressa cretica,Fruit,Screening

Özet: Introduction: The present study was aimed at pharmacognostical, phytochemical, and pharmacological evaluation of Cressa cretica Linn., (fruit) family - Convolvulaceae. Materials and Methods: Pharmacognostical investigation was carried out by performing organoleptic, microscopical, and physicochemical evaluation, i.e.,ash values, extractive values, moisture content, swelling index, foaming index, and foreign matter. The obtained results showed that the moisture content was found to be 2.25%. Similarly, swelling index was recorded to be 0.8 cm. Foaming index (<100). Phytochemical investigation included successive Soxhlet extraction, the obtained extractive values were 1.25%, 0.05%, 5.25%, 29%, and 22.80% for petroleum ether, chloroform, ethyl acetate, ethanol, and distilled water, respectively. The preliminary qualitative phytochemical screening revealed the presence of carbohydrates, phenolic compounds, alkaloids, glycosides, flavonoids, steroids, fixed oils, and fats. Results: Pharmacological investigation included the analgesic activity using C. cretica (fruit) plant ethyl acetate extract when subjected to Eddy’s Hot Plate Model. The obtained results for analgesic activity of C. cretica (fruit) plant extract (ethyl acetate) (100 mg/kg and 200 mg/kg) were found positive.

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