Asian Pacific Journal of Health Sciences

Asian Pacific Journal of Health Sciences

Triazinone Derivatives as Antibacterial and Antimalarial Agents

Yazarlar: Tarawanti Verma, Manish Sinha, Nitin Bansal

Cilt 6 , Sayı 2 , 2019 , Sayfalar 1-20

Konular:-

DOI:10.21276/apjhs.2019.6.2.1

Anahtar Kelimeler:Triazinone,Pyrazole,Antibacterial,Antifungal,Antimalarial,Oxazolone,Hydrazides

Özet: A series of 2,5-disubstituted-3-phenyl-1,2-dihydro-1,2,4-triazin-6(5H)-one derivatives (13(a-g), 18(a-g), 21(a1-a5, 21b) were synthesized using appropriate synthetic route and characterized by spectral data. Synthesized compounds were evaluated for their antimalarial and antimicrobial activities. In vitro antimalarial activity was evaluated against chloroquine-sensitive (3D-7) strains of Plasmodium falciparum by using chloroquine and quinine as standard drung. For antimicrobial activity compounds were tested against four bacteria (Escherichia coli,Pseudomonas aeruginosa, Staphylococcus aureus, Streptococcus pyogenes) and three fungi(Candida albicans, Aspergillus niger, Aspergillus clavatus)using gentamicin, ampicillin, chloramphenicol, ciprofloxacin, norfloxacin and nystatin, griseofulvin as standard drugs, respectively.  

ATIFLAR
Atıf Yapan Eserler
Henüz Atıf Yapılmamıştır
KAYNAK GÖSTER
BibTex
KOPYALA
@article{2019, title={Triazinone Derivatives as Antibacterial and Antimalarial Agents}, volume={6}, number={1–20}, publisher={Asian Pacific Journal of Health Sciences}, author={Tarawanti Verma,Manish Sinha,Nitin Bansal}, year={2019} }
APA
KOPYALA
Tarawanti Verma,Manish Sinha,Nitin Bansal. (2019). Triazinone Derivatives as Antibacterial and Antimalarial Agents (Vol. 6). Vol. 6. Asian Pacific Journal of Health Sciences.
MLA
KOPYALA
Tarawanti Verma,Manish Sinha,Nitin Bansal. Triazinone Derivatives as Antibacterial and Antimalarial Agents. no. 1–20, Asian Pacific Journal of Health Sciences, 2019.
Atıf Görüntüle
PDF Görüntüle
Kaynak Görüntüle
Paylaş
Dergi Bilgileri