Asian Pacific Journal of Health Sciences
Yazarlar: Bapan Banik, Ankita Sharma, Absana Nasrin
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Özet: The present study aimed at the formulation of carminative herbal chewable tablets using herbal constituents. Curcuma longa (turmeric), Foeniculum vulgare (fennel), and Curcuma amada (mango ginger) are the most celebrated herbs in Indian system of traditional medicine. In the present research work, oral chewable tablets were prepared by direct compression and wet granulation method incorporating these three herbs. In both the methods, the powder of turmeric, fennel seed, and ginger mango was prepared initially and it was mixed with additives and preservatives. Physicochemical analysis of the individual drugs, pre-formulation studies, and post-formulation standardization was done to evaluate the quality and purity of the conformation. In the pre-formulation study, it was observed that all the parameters checked for the ingredients were within standard range. Thus, the ingredients were processed for preparing tablets following IP. During the evaluation of tablets, it was found that all the prepared batches of tablets were within the standard range of chewable tablet parameters. Thus, considering these values and following the IP, we found that the chewable tablet that was prepared without altering its therapeutic property was satisfactory with general characteristics of tablet, namely, hardness, disintegration time, friability, and weight variation. The formulation was tested for common people with respect to taste; odor and time required for complete chewing and showed that it can be accepted for the present trends of newer drug delivery dosage forms. The present study provides an approach to come up with a modern outlook to traditional folklore formulations without altering its therapeutic property which is highly essential in industrial applications and to meet consumer preferences and demands. Therefore, it is concluded that the developed chewable tablets may be better alternative to the conventional uses of the herbs.