Asian Pacific Journal of Health Sciences

Yazarlar: Sarika Makwana, Nikhil Mehere, Swapnil Chaudhary, Prashant Bedarkar, Pro Biswajyoti Patgiri, C. R. Harisha

Konular:-

Anahtar Kelimeler:Bakuchi,Gomutra,Pharmacognostical study,Psoralea corylifolia Linn.,Shodhana

Özet: Background: Bakuchi (Psoralea corylifolia Linn.) has immense therapeutic attributes and widely prescribed drug in skin disorders especially Shvitra (vitiligo). Its medicinal usage is found depict in Indian pharmaceutical codex, the Chinese, British and the American pharmacopoeias and in different traditional system of medicines such as Ayurveda, Unani and Siddha. Classic emphasized the Shodhana of Bakuchi seed as pre-treatment before its therapeutic use. Considering this, study was planned for pharmacognostical evaluation of Shodhita and Ashodhita Bakuchi seeds. Materials and Methods: Pharmacognostical study, physicochemical analysis, and psoralen chemical test were performed for the Ashodhita and Gomutra Shodhita Bakuchi seeds powder. Results and Conclusion: Endosperm cells, palisade cells, and trichomes were found disturbed from their normal structure in Ashodhita sample. Oil globules are released from their site. Crystalline structure was observed in Shodhita sample. These changes were found due to the process of alkaline hydrolysis during Shodhana procedure. Alkaline pH (7.4) is found in suspension of Shodhita Bakuchi powder due to employed Shodhana process. Results of ash value, acid insoluble Ash, water-soluble extractives, and alcohol soluble extractives are found within normal limit as described in Ayurveda pharmacopoeia of India. These observations can be of use in future studies.

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