Natural Products and Biotechnology

Yazarlar: Mehmet Özgür Atay, Buse Ardıl, Mehlika Alper, Olcay Ceylan

Konular:-

Anahtar Kelimeler:Ornithogalum nutans,Sternbergia lutea,Allium stylosum,Artemia salina,Anthelmintic activity

Özet: In this study, toxic and anthelmintic activities of methanol extracts of aerial and underground parts of Ornithogalum nutans L., Sternbergia lutea (L.) Ker-Gawl. ex Spreng. and Allium stylosum O.Schwarz were investigated. In order to determine the anthelmintic activity, the time elapsed for the duration of paralysis and death was determined after the extracts of different concentrations (10, 20 and 30 mg/mL) were added to the Tubifex tubifex in petri dishes. Each concentration of A. stylosum aerial and underground parts extracts showed high anthelmintic activity. In addition, aerial extract of O. nutans at a concentration of 30 mg/mL showed high anthelmintic activity. A. stylosum extracts showed a higher activity than the standard anthelmintic drug. The toxic activity was determined against Artemia salina with brine shrimp lethality test. Among all extracts, the underground extract of S. lutea showed the highest activity with 0.002 mg/mL, LC50, the aerial extract of O. nutans showed the lowest activity with 0.03 mg/mL, LC50. Aerial and underground methanol extracts of A. stylosum showed high anthelmintic and lethal activity, but more specific studies are needed.

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