ADMET & DMPK

Yazarlar: ["Matthias Fellner"]

Konular:-

DOI:10.5599/admet.1137

Anahtar Kelimeler:Inhibitor,Biofilm,Fluorophosphonate

Özet: There is an urgent need for new diagnosis and treatment options for the bacterial pathogen Staphylococcus aureus. This review will summarize data on ten recently discovered biofilm-associated serine hydrolases called fluorophosphonate-binding hydrolases (FphA-J). Based on the summarized findings, many of these proteins represent intriguing new targets for probe and drug development.

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