ADMET & DMPK
Physiologically based pharmacokinetic (PBPK) modeling and simulation in drug discovery and development
Yazarlar: Abdul Naveed Shaik, Ansar Ali Khan
Cilt 7 , Sayı 1 , 2019 , Sayfalar 1-3
Konular:-
DOI:10.5599/admet.667
Anahtar Kelimeler:Physiologically based pharmacokinetic modeling,PBPK
Özet: Physiologically based pharmacokinetic (PBPK) modeling is a mechanistic or physiology based mathematical modeling technique which integrates the knowledge from both drug-based properties including physiochemical and biopharmaceutical properties and system based or physiological properties to generate a model for predicting the absorption, distribution, metabolism and excretion (ADME) of a drug as well as pharmacokinetic behavior of a drug in preclinical species and humans.
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BibTex
KOPYALA
@article{2019, title={Physiologically based pharmacokinetic (PBPK) modeling and simulation in drug discovery and development}, volume={7}, number={1–3}, publisher={ADMET & DMPK}, author={Abdul Naveed Shaik, Ansar Ali Khan}, year={2019} }
APA
KOPYALA
Abdul Naveed Shaik, Ansar Ali Khan. (2019). Physiologically based pharmacokinetic (PBPK) modeling and simulation in drug discovery and development (Vol. 7). Vol. 7. ADMET & DMPK.
MLA
KOPYALA
Abdul Naveed Shaik, Ansar Ali Khan. Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulation in Drug Discovery and Development. no. 1–3, ADMET & DMPK, 2019.