Acta Materialia Turcica

Acta Materialia Turcica

Synthesis, Characterization and Biological Activities of Novel a 1,2,3,4-tetrahydroquinazoline and Its Nickel(II) Complexes

Yazarlar: Alper ÇOLAK, Murat TAŞ, Gazi İREZ, Orhan BÜYÜKGÜNGÖR, Ferdağ ÇOLAK, Handan GÜNAY

Cilt 1 , Sayı 1 , 2017 , Sayfalar 11 - 19

Konular:Mühendislik, Kimya

Anahtar Kelimeler:Antimicrobial activity,Nickel complex,Oxime,1,2,3

Özet: The 2-methyl-2-(1-hydroxyiminoethyl)-1,2,3,4-tetrahydroquinazoline (HL or 1) and its novel Ni(II) complexes, square-planar [Ni(L)(LH)]·(NO3) (2) and octahedral [NiCl2(LH)(H2O)2]·(H2O) (3), have been synthesized. The ligand and complexes have been characterized by means of elemental, IR, UV-Vis. spectroscopic studies, 1H-NMR, 13C-NMR, magnetic susceptibility, thermal analysis, mass spectroscopy and X-ray diffraction technique. The HL ligand crystallizes in the P21/c. Antimicrobial activity of ligand (1) and complexes (2 and 3) was evaluated by the agar diffusion method. Complex 2 showed weak antimicrobial activity against tested microorganism strains. Complex 3 exhibited moderate antimicrobial activity against Staphylococcus epidermidis and Candida albicans.

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@article{2017, title={Synthesis, Characterization and Biological Activities of Novel a 1,2,3,4-tetrahydroquinazoline and Its Nickel(II) Complexes}, volume={1}, number={1}, publisher={Acta Materialia Turcica}, author={Alper ÇOLAK,Murat TAŞ,Gazi İREZ,Orhan BÜYÜKGÜNGÖR,Ferdağ ÇOLAK,Handan GÜNAY}, year={2017}, pages={11–19} }
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Alper ÇOLAK,Murat TAŞ,Gazi İREZ,Orhan BÜYÜKGÜNGÖR,Ferdağ ÇOLAK,Handan GÜNAY. (2017). Synthesis, Characterization and Biological Activities of Novel a 1,2,3,4-tetrahydroquinazoline and Its Nickel(II) Complexes (Vol. 1, pp. 11–19). Vol. 1, pp. 11–19. Acta Materialia Turcica.
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Alper ÇOLAK,Murat TAŞ,Gazi İREZ,Orhan BÜYÜKGÜNGÖR,Ferdağ ÇOLAK,Handan GÜNAY. Synthesis, Characterization and Biological Activities of Novel a 1,2,3,4-Tetrahydroquinazoline and Its Nickel(II) Complexes. no. 1, Acta Materialia Turcica, 2017, pp. 11–19.
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