Türk Bilimsel Derlemeler Dergisi
Yazarlar: Gözde IŞIK, Şayeste DEMİREZEN, Mehmet Sinan BEKSAÇ
Konular:-
Anahtar Kelimeler:Apoptosis ,Cervical carcinoma,Infl ammation,Tumor necrosis factor.
Özet: Tumor necrosis factor (TNF), which causes tumor necrosis, is a cytokine that also plays role of infl ammationand apoptosis processes. TNF, secreted priorly by macrophage any many other cells in reactions such as allergyand infl ammation, plays essential roles in innate immunity. The latest works indicate that while TNF inducestumor necrosis for example cervical tumors, it also increases to tumor growth. It is reported that a decrease inTNF secretion causes the development of cancer cells whereas an increase in TNF secretion leads to apoptosisor necrosis. This review is planned in order to clarify the biological activities of TNF and its relationship withcervical tumors.