Türk Bilimsel Derlemeler Dergisi

Yazarlar: Mine DOSAY AKBULUT, Elvan AKGÜL

Konular:-

Anahtar Kelimeler:Shark,Cartilage,Liver oil,Cancer.

Özet: Cancer has been seen rarely or none in sharks, compare to the other organisms, and it is important to understand what the relationship ofthe shark's cancer-preventing immune system is that? A lot of different suggestions were made by the scientists. One of the important mainexplanation in that, the sharks cartilage and liver oil effections’ against to the cancer formation. There are a lot of reasons to being cancer.But mainly, depends on the blood vessel developing status. One of the main differences between sharks and higher vertebrates; is that ashark's skeleton is made of cartilage. Cartilage is different from other types of tissue, meaning it does not contain any blood vessels. Recentresearch indicates there is a relation between the lack of blood vessels in shark cartilage and sharks anti cancer mechanism. It was determinedthat shark cartilage is a powerful inhibitor of tumor growth. Another important differences in sharks that their almost 10 times higher amountof liver oil content, compare to the other animals. The effective parts of shark liver oil have been determined as a group of ether-linkedglycerols or in other saying alkylglycerols. The activation of protein kinase C, having a role in cell proliferation, can be prevented byalkylglycerols. Different studies indicated that, alkylglycerols have a multifunctional role and shark liver oil can be used in treatment ofseveral types of cancer.

---