Experimental and Applied Medical Science

Yazarlar: Nuray SATILMIŞ, Leyla ÇİMEN, İhsan ÇETİN ÇETİN, Yahya POLAT, Behzat ÇİMEN

Konular:Tıp

Anahtar Kelimeler:Childhood obesity,Oxidative stress,Antioxidant,Regular exercises,Carbonyl

Özet: It is unclear how aerobic exercise program effects oxidative stress and antioxidant defense parameters in obese children; therefore, our objective is to examine the effects of aerobic exercise on parameters of oxidative stress and antioxidant in obese boys. Our study included 10 obese boys, aged from 13 to 15, and 10 healthy boys as control group. Before and after exercise, 10 ml blood specimens were taken from the obese boys, who exercised 3 days/week for 12 weeks. 10 ml blood specimens were also taken from the health control group. The oxidative stress and antioxidant defense parameter levels in blood samples were measured for both groups. In our study, it was found that control group and obese children after aerobic exercise had significantly higher superoxide dismutase, catalase, glutathione peroxidase and paraoxonase-1 values than those of obese boys before aerobic exercise. On the other hand, it was found that after aerobic exercise, control group and obese children had significantly lower malondialdehyde, nitric oxide and carbonyl values than those of obese boys before aerobic exercise. When these findings are taken into account, it may be suggested that aerobic exercise regulated oxidative stress and improved the state of antioxidant status in obese boys.

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