Anatolian Journal of Biology

Yazarlar: Furkan ÇOLAK, Mucip GENİŞEL, İbrahim Seyda URAS

Konular:Biyoloji

Anahtar Kelimeler:Glycyrrhiza,Therapeutic Agent,Phenolic Compounds,Antiviral,Antioxidant

Özet: In this study, Glycyrrhiza species cultivated in Turkey assessed in terms of their chemical composition, morphological features and therapeutic activities. Potassium and calcium salts including licritic acid, gylcertatol and glycyrrhic acid have been found in the roots. Glycyrrhizin, a cough suppressor and natural antioxidant, has been determined as major triterpenoid saponin found in roots. Studies revealed that leaves contain flavonoids which have antioxidant and anti-inflammatory effect. Glycyrrhiza species have economic value due to their compounds with different bioactivities such as antioxidant, anti-inflammatory, antimicrobial activity. In recent studies, besides of known therapeutic effects of active compounds obtained from Glycyrrhiza species, it has been investigating whether they have a neuroprotective effect for Alzheimer's disease therapy. In the light of the data in the literature, it has also been revealed side effects of active compounds in this plant species. On the other hand, the side effects of active compounds isolated from these species have been manifested with various data. To find their new bioactive compounds against different diseases, studies on Glycyrrhiza species should be increased.

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