ADO Klinik Bilimler Dergisi

Yazarlar: Ayaz ENVER, Nurdan ÖZMERİÇ

Konular:Diş Hekimliği

Anahtar Kelimeler:Cytokines,Inflammatory Bowel Diseases,Periodontal Diseases

Özet: Periodontal disease is a local, chronic and inflammatory process that resulted from a complex interactions between biofilm and inflammatory immune response. Biofilm infections generally cause simultaneous activation of both natural and adaptive immune responses. Inflammatory bowel diseases characterized by chronic inflammation in the intestines with exacerbations and remissions. Although the etiopathogenesis is not fully known, it is suggested that the disease is caused by chronic immune-mediated intestinal damage as a result of the complex interaction of genetic susceptibility and endogenous and exogenous triggers. Cytokines take a place in many events including proliferation, growth, differentiation, hemostasis, regeneration, repair and inflammation. We aim in this review to evaluate the studies dealing with periodontal disease, inflammatory bowel diseases and their relation by emphasizing the role of cytokines. Keywords: Cytokines; Inflammatory bowel diseases; Periodontal disease.

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