The Journal of Neurobehavioral Sciences
Yazarlar: Can Akpinaroglu , Korkut Ulucan
Konular:-
DOI:10.5455/JNBS.1494416158
Anahtar Kelimeler:-
Özet: Trichotillomania can be described as a psychiatric disorder where a recurring hair pulling behaviour is observed in an individual.Neurobiological causes of this condition is still unclear. Because of this, definite solutions can not be presented in the treatment.Molecular genetic studies are of great importance for a better understanding of the etiology of trichotillomania and for the treatmentof this disorder. As of today, our knowledge and information about trichotillomania is limited. The molecular analyzes madesuggest that HOXB8, SAPAP3, DRD1, DRD4, SLC6A4 genes may be related to the disease. In this review, the psychological andphysiological basis and classification of trichotillomania will be followed by genetic polymorphisms that are thought to be related tomolecular genetic studies, animal studies and disorders of trichotillomania. We hope that this article will also guide to the furthermolecular studies that can be carried out in this subject.