Acta Medica

Acta Medica

Vitamin D and Parathyroid Hormone Levels in Prediction of the Prevalence of Cerebrovascular Accident in Geriatric Patients

Yazarlar: uammedCemalKızılarslanoğlu, emetEminKuyumcu

Cilt 45 , Sayı 1 , 2014 , Sayfalar -

Konular:-

Anahtar Kelimeler: Vitamin D,Hyperparathyroidism,Parathyroid Hormone,Stroke

Özet: Background: Plasma 25- (OH) Vitamin D level and various disorders such as metabolic syndrome, type 2 diabetes mellitus, cardiovascular problems, dementia, chronic renal disease, chronic pulmonary disease, colorectal can- cer were shown to be associated. However, recent studies indicate that para- thyroid hormone (PTH) may also have an impact on the development of aforementioned disorders. In this study, we aimed to investigate plasma vi- tamin D and serum PTH status and cerebrovascular accident association in the elderly. Material and Methods: Totally, 1078 adult patients aged 65 year-old or old- er (103 patients with a past medical history of stroke and 975 patients with- out stroke history) were included in this cross sectional study. After compre- hensive geriatric assessment, laboratory investigations including plasma vi- tamin D and serum PTH levels were evaluated. Results: The median of plasma 25- (OH) Vitamin D levels (16.28 vs. 18.00 ng/ml) was significantly lower and the median of serum PTH levels (58.7 vs. 54.9 pg/ml) was significantly higher in patients with stroke than in patients without his- tory of stroke group (P=0.016 and P=0.019, respectively). Multivariate regres- sion analysis revealed that only serum PTH level (OR=1.007, 95% CI=1.002- 1.012, P=0.007) was an independent variable for stroke. Conclusion: Our study supports the assumption that elevated PTH has a role in stroke risk stratification. We would like to emphasize that serum PTH level -even though it is in the reference range- may be a predictor of cardio- vascular outcomes such as cerebrovascular accident in the elderly.

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@article{2014, title={Vitamin D and Parathyroid Hormone Levels in Prediction of the Prevalence of Cerebrovascular Accident in Geriatric Patients}, volume={45}, publisher={Acta Medica}, author={Muhammed Cemal Kızılarslanoğlu, [MD] (Author); Mehmet Emin Kuyumcu, [MD]}, year={2014} }
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Muhammed Cemal Kızılarslanoğlu, [MD] (Author); Mehmet Emin Kuyumcu, [MD]. (2014). Vitamin D and Parathyroid Hormone Levels in Prediction of the Prevalence of Cerebrovascular Accident in Geriatric Patients (Vol. 45). Vol. 45. Acta Medica.
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Muhammed Cemal Kızılarslanoğlu, [MD] (Author); Mehmet Emin Kuyumcu, [MD]. Vitamin D and Parathyroid Hormone Levels in Prediction of the Prevalence of Cerebrovascular Accident in Geriatric Patients. no., Acta Medica, 2014.
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