Cumhuriyet Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi

Yazarlar: Sevin COŞAR AYAZ, Hasanali DURMAZ, Mehmet Ercüment DÖĞEN

Konular:-

Anahtar Kelimeler:Fluorodeoxyglucose F18,Positron-emission tomography/computed tomography,Stomach neoplasms,Neoplasm metastasis,Liver

Özet: Abstract [18F]-2-fluoro-2-deoxy-D-glucose (FDG) positron emission tomography (PET)/ computed tomography (CT) imaging is being performed for staging, restaging and evaluation of response to treatment in gastric cancer. In FDG PET/CT imaging, metabolic parameters of the primary tumors and their metastases, namely the maximum standard uptake value (SUVmax) and the tumor lesion glycolysis (TLG) are evaluated. In this retrospective study, we aimed to obtain and compare the metabolic parameters of the primary tumors and their liver metastases in patients with gastric cancer who underwent FDG PET/CT imaging and who didn’t undergo surgery. Eleven patients (six females, five males) were included in the study. SUVmax and ve TLG values of the primary tumors and their liver metastases (n=24) were obtained and compared using independent sample t-test. The mean SUVmax of the primary gastric tumors and their liver metastases were 8.3±3.3 ve 7.6±1.8, respectively (P<0.05). The mean TLG of the primary gastric tumors and their liver metastases were 84.7±60.2 ve 127.9±39.7, respectively (P<0.05). There were significant differences between metabolic parameters of the primary tumors and their liver metastases. Since the mean TLG value of the liver metastases were higher than that of the primary tumor, taking TLG values into account beside SUVmax values were considered to make significant contribution to FDG PET/CT evaluation of these cases. FDG PET/CT is an effective tool in obtaining metabolic parameters of primary gastric malignancies and their liver metastases. 

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