Anka Tıp Dergisi

Yazarlar: Ali SEYED RESULİ

Konular:Kulak, Burun, Boğaz

Anahtar Kelimeler:Tonsillectomy,Chronic tonsillitis,Free oxygradicals

Özet: Aim and Background: Today, tonsillectomy (T) used for chronic tonsillitis is among the most common surgery type that ear, nose, and throat physicians perform. The differences in the pathogenesis of chronic tonsillitis and tonsil hypertrophy are still unknown. This study aimed to compare the levels of free oxygen radicals in patients with tonsil hypertrophy and chronic tonsillitis and to investigate the role of free oxygen radicals in the pathogenesis of chronic tonsillitis. Materials and Method: The study included 40 patients who had chronic tonsillitis indications based on Paradise criteria, and T was performed. Operation materials were histopathologically examined, and their free oxygen radicals (FOR) levels were measured. Results: Based on the histopathological results, the participants were divided into two groups: one including 28 (70%) patients who had active or chronic tonsillitis, the other including 12 (30%) patients with reactive follicular hyperplasia.  Lucigenin - free oxygen radicals (Luc-FOR) levels of the group with chronic tonsillitis and that of the group with reactive follicular hyperplasia were 82.29±32.3 Auc and 50.76±7.95 Auc, respectively.  Luc-FOR values were found to be significantly higher in the group with chronic tonsillitis (p=0.001). Conclusion: Free oxygen radicals play an essential role in tonsillar pathologies. Differences in the Luc-FOR levels measured from tonsillar tissue in patients with tonsil hypertrophy and chronic tonsillitis demonstrate that the pathogenesis of these two diseases is different.

---