Anka Tıp Dergisi
Yazarlar: Şirin ÇELİK, Nahide ONSUN, Özlem SU KÜÇÜK
Konular:Dermatoloji
DOI:10.38175/phnx.742858
Anahtar Kelimeler:Psoriasis,Psoriasis Area and Severity Index,Psoriasis Scalp Severity Index,Nail Psoriasis Severity Index
Özet: Aim Psoriasis is a chronic immune-mediated skin disease that can progress with skin, nail, and joint involvement. Skin lesions adversely affect the life quality due to both itching and development of aesthetical anxiety. Nail and joint lesions also reduce life quality in terms of aesthetics and functionality. Our study aimed to determine the relationship between the severity of scalp and nail involvement with the severity of skin lesions in psoriasis patients. Materials and Methods This prospective study included a total of 267 psoriasis (plaque and guttate type) patients aged between 18 and 70 years old who were being followed up and treated at the psoriasis outpatient clinic between 2010 and 2011. The psoriasis severity index was calculated to determine the disease severity of these patients who were diagnosed clinically or histopathologically. Scalp involvement severity was assessed by the Psoriasis Scalp Severity Index, and the Nail Psoriasis Severity Index scoring evaluated nail involvement severity. Correlation between variables was evaluated with the Pearson correlation test, and the difference between these correlations was assessed with the Z test. Results Of the 267 patients included in the study, 135 were male, and 132 were female. The mean age of the patients was 43.64 (18-70). Of the patients, 106 received topical therapy, 103 received systemic treatment, 53 received biological agent therapy, and five received phototherapy. While 173 of the patients had a plaque, and 84 had guttate lesions, ten did not have lesions. A significant relation was found between the psoriasis severity index values and the Psoriasis Scalp Severity Index values of patients (p <0.001). A meaningful relationship was found between the psoriasis severity index values and the Nail Psoriasis Severity Index values of patients (p <0.001). However, no significant relation was found between the Psoriasis Scalp Severity Index values and the Nail Psoriasis Severity Index values of patients (p = 0.440). Conclusion: As the clinical severity of the disease increases in psoriasis patients, the scalp and nail involvement severity increases. There is no relationship between the severity of scalp involvement and nail involvement.