International Journal of Health and Clinical Research

Yazarlar: Jay Satish Bhatt, Naveen Rathor

Konular:-

Anahtar Kelimeler:Uric acid,Tophus,Tendon.

Özet: Background:The worldwide prevalence of hyperuricemia and burden of gout is reportedly increased in last few decades. Serum uric acid levels above threshold levels result in nucleation of monosodium urate (MSU) crystals and leads to deposition of crystals in tissues and around joints among cases of long-standing hyperuricemia. However, subclinical inflammation always precedes the deposition of crystals and other manifestation of gout. Material & Methods: In the present study 200 Patients who were diagnosed with gout by ACR (American College of Rheumatology) criteria were enrolled for the study by simple random sampling. Clearance from Institutional Ethics Committee was taken before start of study. Written informed consent was taken from each study participant. Results: In the present study, 112 (56%) patients the serum uric acid levels were found more than 7 mg/dl. Out of these patients 34 (30.4%) were previously diagnosed with high serum uric acid (more than 7 mg/dl). We found that intra-tendinous tophus is most common in patellar tendon among 18 (9%) patients which is followed by involvement of quadriceps tendon among16 (8%) patients and involvement of Achilles tendon and peroneus tendon among 6 (3%) cases respectively. tophi in both quadriceps and Achilles tendon among14 (7%) patients which is followed by involvement of both quadriceps and patellar tendon among 10 (5%) patients and 6 (3%) patients had involvement of both patellar and Achilles tendon.Conclusion: We concluded from the present study that the ultrasound examination and all the hyperechoic aggregates of intra-tendinous tophus was the most common presentation among tendons of lower limb. Involvement of patellar tendon was the most common presentation which is followed by Quadriceps and Achilles tendon.   Key words:Uric acid, Tophus, Tendon.

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