International Journal of Health and Clinical Research
Yazarlar: Trupti Patil, Smita P. Bhide, Sneha R. Joshi
Konular:-
Anahtar Kelimeler:Cervix,Histopathology,Alignancy
Özet: Introduction:The cervix is elongated fibro muscular portion of the uterus, it measures 2.5 to 3.0 cm.Uterine cervix acts as a "gateway" for various infections, which affects cervix, uterus and upper genital tract, leading to cause various lesions of cervix as well as acting as a sentinel for upper genital tract infections and a target for viruses and other carcinogens, which may lead to invasive carcinomas.Aims and objectives :1.To study the occurrence & age distribution of various lesions of cervix. 2. To study and classify cervical lesions histopathogically. 3. To study the occurrence of histopathogical variants of carcinoma of cervix.Materials and methods:Present study was a prospective study conducted in the Dept of Pathology during the period of October 2016 to August 2018. The study involved analysis of specimens received in histopathology laboratory of Dept of Pathology from Dept of OBGY in the form of hysterectomy, cervical biopsy & cervical polypectomy.Results :The present study was a prospective study done over a period of two years from October 2016 to August 2018. In this study a total of 288 uterine cervical specimens were studied. Out of these specimens, Inflammatory lesions formed the major part accounting to 74.30%, followed by Malignancies (13.54%).Among the Inflammatory cervical lesions, Chronic non specific cervicitis was the most common in 188/214 (87.86%) cases. Benign cervical lesions were found in 19/288 (6.59%) cases. Total 39/288 (13.54%) cases of Invasive cervical malignancies were encountered. Among cervical malignancies, Squamous cell carcinoma was the commonest in 36/39 (92.32%) cases. Of these Large cell non keratinizing was the most common histological subtype.Conclusion :Cervical malignancies are most common malignancies of female genital tract Histomorphological studies of the cervix along with clinical correlation is very important for early diagnosis in diseases of the cervix as they have advantage of being readily available, relatively cheap and technically easy. Histopathological examination of biopsy specimen is the single best gold standard for the diagnosis.