International Journal of Health and Clinical Research

Yazarlar: Dinesh J Vyas, Satish Kumar Gupta, Swati Jangir, Atul J Rajpara

Konular:-

Anahtar Kelimeler:Essential Fatty Acids (EFA),Flax Seed Oil,Rhumatoid Arthritis

Özet:   Introduction: Rheumatoid arthritis is a chronic and progressive illness that has the potential to cause joint destruction and functional disability. Early medical intervention has been shown to improve outcomes and function and stops damage to joints.  Omega 3 fatty acids are shown to have anti-inflammatory action.Objectives: The present study was planned to evaluate efficacy, tolerability and safety of flaxseed oil supplementation in in patients of Rheumatoid arthritis.Material and methods: The study was randomized, Placebo controlled, single blinded study at Department of Orthopaedics of a tertiary care teaching hospital and private orthopaedic hospital in Gujarat. Enrolled patients received flaxseed oil or placebo over a period of six weeks. Clinical features, laboratory investigations and adverse reactions were recorded and compared with baseline values.Results: Flaxseed oil supplementation was associated with a greater improvement in symptoms and joint function after six weeks of treatment as compared to placebo group. Also, tolerability of flaxseed oil was similar to the placebo group.Conclusion: Flaxseed oil supplementation may have a beneficial effect in patients of Rheumatoid arthritis. Further large-scale studies are recommended to evaluate the role of flaxseed oil supplementation in Rheumatoid Arthritis.

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