International Journal of Health and Clinical Research
Yazarlar: G. Prathima, U. Syam Sunder Rao
Konular:-
Anahtar Kelimeler:Thrombocytopenia,Dengue,ITP(IdiopathopathicThrombocytopenia)
Özet: Introduction: Thrombocytopenia is a common clinical condition with a wide variety of etiological causes. This may result from reduced development of platelets, increased destruction of platelets and differentiation in the distribution of platelets. While temporary suppression of the bone marrow and invasion of the marrow by malignancies are important causes, certain non-malignant conditions, such as infections and medications, are equally important as their treatment is easy and full recovery is the norm. Accurate aetiology identification is critical for specific treatment and prognosis.Aims: To study of thrombocytopenia clinical results in patients diagnosed with thrombocytopenia.Materials and methods:The prospective study was carried out at the department of Pathology, Fathima Medical College, Kadapa, Andhra Pradesh, during the period from January 2017 to June 2020. A total of 90 patients for whom bone marrow aspiration was recommended were included. At the time of diagnosis, the age of the study group ranged from 6 months to 80 years.Results: In our study out of 90 patients 29(32%) patients were dengue positive and 61(68%) were dengue negative, with male female ratio of 3:2. The age of the study group ranged from 6 months to 80 years. Most of the patients in study are seen in age 11-20 years (36.7%) followed by 21-30 years (16.7%). Most of the patients in study presented with epistaxis (15.6%)followed by rash (14.4%). In study are of Mild (46%) forms followed by sever(30%). The most common cause for thrombocytopenia in this study was dengue infection seen in 29 cases(32%). ITP in 22 cases(24.4%) followed by chronic liver disease in 16 cases(17.8%), post-medication in 9 cases(10%), gestational in 7 cases(7.8%).Conclusion: In our study leading cause of thrombocytopenia is preventable and treatable. The frequency of thrombocytopenia would therefore be minimised by raising socioeconomic status and avoiding infection.