International Journal of Health and Clinical Research
Yazarlar: Mayank Goyal, Kamal K. Sen, Sangram Panda, Jagadeesh K, Roopak Dubey, Rohit Arora, Manoj K, Arun Kumar
Konular:-
Anahtar Kelimeler:COVID,9,Pediatrics,Adults,Geriatrics,HRCT chest
Özet: Background: Coronavirus Disease 2019 (COVID-19), a severe acute respiratory syndrome documented as a pandemic by WHO, known to affect patients of all ages.Purpose: The purpose of our study is to characterize the HRCT chest features of COVID-19 patients and analyze the imaging pattern inpediatric, adult and geriatric patients.Materials and Methods: A cohort study of 1208 laboratory-confirmed COVID-19 and HRCT positive patients were undertaken, between May 1, 2020 to July 31, 2020. Patients were divided into 3 groups: Pediatric patients (6 to 18 years), Adults (18 to 60 years) and Geriatric patients (older than 60 years). The demographic, clinical, laboratory and HRCT chest findings were assessed and analyzed between the three groups.Results: A total of 1208 patients with laboratory confirmed COVID-19 infections were assessed. There was a male predominance overall with statistical difference where males are more common affected in adults (86.6%) in compare to pediatric (71%) and geriatric patients (70%). Most of the patients were asymptomatic or had mild symptoms, fever was the most common clinical presentation in pediatric (46.5%), adults (44%) and geriatric patients (52.8%). Increased C-reactive protein was noted in all the three groups with p-value<0.05. Geriatric patients have higher CT positivity (97.1%) and CT severity (10.59±6.7) in comparison to pediatric (66.6%, 4.04±4.6) and adult patients (79.4%, 5.96±6.5). Bilateral and peripheral sub-pleural distribution of pulmonary opacities was the most common pattern seen in both adults and pediatric groups, 56.7% and 50% respectively while diffuse and peripheral distribution predominance in geriatrics (45%) Conclusion: Pediatric, adult and geriatric patients showed distinctive clinical and CT chest finding with pediatric patients have relatively milder symptoms with higher prevalence of negative CTs and lesser extension on imaging while geriatric patients have more symptoms with higher prevalence of positive CTs and more extensive involvement in comparison to adult patients. Keywords: COVID-19, pediatrics, adults, geriatrics, HRCT chest