International Journal of Health and Clinical Research
Yazarlar: Vikas Saxena, Jyoti Batra, Tapan Mohapatra, Shashi Saxena, Anurag Agarwal
Konular:-
Anahtar Kelimeler:ABG,LoodpH,OPD,CVD,PCO2,PO2.
Özet: Background:Chronic Obstructive Pulmonary Disease (COPD) is a complex respiratory disease. Which is notorious for producing many comorbidities. This disease produces chronic inflammatory changes in the lungs which ultimately leads to cardiovascular and other associated diseases causing raised mortality and morbidity.COPD also leads to change in various biochemical parameters like atrial blood gas, serum electrolytes, etc. These changes may produce fatal effects on the heart with dangerous sequela. In the present study, we had tried to correlate these parameters to elucidate the magnitude of the relation between these two diseases. It was observed that heart disease is the most common comorbidity in patients with COPD. Aim: To study about the alteration in blood pH, blood gases, and serum electrolytes in COPD patients. To find out their correlation between COPD and CVD.Materials and Methods: A hospital-based study was done on confirmed 109 COPD patients based on spirometry. With these patients, arterial blood gas analysis was done to find out the blood pH, PO2, and PCO2 level along with serum electrolytes. Further echocardiography was carried out to confirm the cardiovascular disease among COPD patients. Results: In this study, the numbers of patients with moderate, severe, and very severe COPD were 35.78%, 45.87%, and 18.35% respectively. On echocardiography with COPD patients, 57(52.29%) cases had normal echocardiograph. While 52 patients (47.71%) were found with pulmonary arterial hypertension, 33 patients (30.28%) with dilated RA/RV, 25 patients (22.94%) with LVDD, and 24 patients (22.02%) with low LVEF. Conclusion: We found that there is a strong correlation between COPD and CVD.COPD if not treated or controlled at the early stage may lead to CVD, which is more dangerous than COPD. Biochemical parameters in our study show a strong statistical correlation between these two diseases.