International Journal of Health and Clinical Research

Yazarlar: Vinay Kumar Sayeli, Madhav P, Vijay Kumar Sayeli, Ankireddy palli Kameswar Reddy

Konular:-

Anahtar Kelimeler:TB treatment,Adverse effects of anti,Ubercular drugs,Non,Ompliance to anti,Ubercular therapy,Category,1 anti,B drugs

Özet: Background: Poor compliance to anti-tubercular therapy by patients with tuberculosis leads to drug resistance and decreases the cure rates in patients. This study is aimed at understanding the safety pattern of adverse drug reactions with Cat-1 anti-tubercular drugs in our locality. This study is also aimed to understand the chances of non-compliance to anti-tubercular therapy due to adverse drug reactions of anti-tubercular drugs. Materials and Methods: This study is a cross-sectional study done on 200 patients who received Cat-1 anti- TB treatment regimen at a RNTCP centre in District Government Hospital, Chittoor. Adverse drug reactions experienced during treatment by the patients were enquired. Prevalence of adverse drug reactions and their contribution to non-compliance of anti-tubercular therapy has been captured using a questionnaire.Results: Prevalence of adverse drug reactions was 32% in patients receiving Category-1 anti-tubercular treatment, and prevalence for the chances of non-compliance is 8 % due to these adverse drug reactions. This study also concludes that vertigo, visual disturbances, rashes, yellowish discolouration of the sclera and joint pain are the adverse drug reactions that can significantly contribute to chances of non-compliance.

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