International Journal of Health and Clinical Research

Yazarlar: Tejaswi Reddy, Paramesh Pandala, Mallareddy Ponnathota, Alimelu Madireddy, Rakesh Kotha

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Anahtar Kelimeler:-

Özet: As we know COVID-19, caused by SARS-CoV-2, is a global public health crisis. Due to the lack of viral receptors in children's lungs and placenta, children and newborns are fortunately less affected. But sometimes maternal antibodies may cause severe inflammation in neonates in the form of  Multisystem inflammatory syndrome (MIS-N). Spike protein antibodies which are usually increased after immunization are protective. These antibodies cross the placenta to provide passive immunity to the newborn. Autoantibodies against endothelial, gastrointestinal, and immune cells are may potentially play a role in MIS-N. Here we are presenting atypical presentations of MIS-N. The role of genetic susceptibility in the pathogenesis of MIS-N needs further investigation.

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