International Journal of Health and Clinical Research
Yazarlar: Subhash Kamareddy, Abhijit S Shetty, Praveen M Pawar
Konular:-
Anahtar Kelimeler:Acute pancreatitis,Severe necrotizing disease,Multi,Rgan dysfunction,Death.
Özet: Introduction: Acute pancreatitis is the acute inflammation of pancreatic parenchyma which varies from a mild form to severe necrotizing disease. Most of the episodes are mild and self limiting which subside spontaneously within a few days. In contrast, an ongoing inflammatory process will lead to severe acute pancreatitis in about 15-20% of cases1. Severe acute pancreatitis has high morbidity and mortality because of systemic inflammatory changes causing SIRS which will lead to multi-organ dysfunction and death. Materials and Methods: A Cross-sectional study was conducted in Inpatients in the General Surgery department, Justice K.S. Hegde Charitable Hospital, of K.S. Hegde Medical Academy, a unit of Nitte (Deemed to be University), Deralakatte, Mangalore. Using EPi info software version 3.01, the minimum sample size required for the study was calculated. Patients diagnosed with AP are categorized into mild, moderately severe, and severe according to Revised Atlanta Criteria. Results: Among 94 subjects mild, moderately severe, severe AP was observed in 76,11,7 patients respectively, among them patients aged between 31-40 had the highest incidence in all three groups of AP. We observed that of 94 subjects, 43(42.7%) subjects had hospital stay between 5-10 days, and 20 (20.7%) subjects,31(33.7%) subjects had a hospital stay of <5days,and >10days respectively with a p-value of 0.001. Conclusion: Our study demonstrates that serum PCT could not significantly predict the severity of Acute Pancreatitis. We determined serum PCT levels in predicting the severity of AP. There was a male preponderance in the study group (88%). Most of the study subjects were in the 31-40 years group. The majority of the patients had mild AP (76 patients). The majority of the patients had Alcohol-induced AP (58.7%). No statistical significance was found between the serum PCT levels and severity of AP, a p value of 0.218.