International Journal of Health and Clinical Research

Yazarlar: Shahid Hassan, Md. Ainul Haque

Konular:-

Anahtar Kelimeler:Pityriasis versicolor,Luliconazole,Ketoconazole,Clinical efficacy,Age group,Gender

Özet: Objectives: This study was to evaluate the clinical efficacy of 1% topical luliconazole versus 2% topical ketoconazole in pityriasis versicolor patients. Methods: Detail assessment and clinical examinations were performed to all patients of pityriasis versicolor.Mycological examination of all the patient was done by using skin scrapings were collected from the skin lesions to prepare for 10% KOH mount, which was examined under the microscope to note the findings as KOH mount positive or negative for Malassezia fungi. KOH mount positive or negative was noted at 0 days, 2 weeks and 4 weeks continued treatments with luliconazole and ketoconazole group patients. Results: Most of the cases were males (65%). Male and female ratio was 13:7. Majorities of patients (51%) were belonged in age group of 26-35 years. At the first days (beginning of treatment), majorities of patients 46(92%) of luliconazole group were positive for KOH mount. At 14 days treatment with luliconazole, patients had 11(22%) positive for KOH mount. And at the 28 days treatment with luliconazole, only 2(4%) patients were positive and most of the patients 49(98%) were negative for KOH mount. Similarly, in ketoconazole group patients, 47(94%) patients were positive for KOH mount in beginning of treatment. At 14 days treatment with ketoconazole 16(32%) patients were positive and 34(68%) patients were negative for KOH mount. And at the 28 days with treatment of ketoconazole 13(26%) patients were positive and most of the patients 37(74%) were negative for ketoconazole. Conclusions: Male population as well as age group 26-35 years were more prone to pityriasis versicolor infection. On two weeks of treatment luliconazole and ketoconazole had near about similar efficacy against pityriasis versicolor patients. But, on continue 4 weeks of treatment regimens topical luliconazole had more clinically efficacious than ketoconazole against pityriasis versicolor.

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