International Journal of Health and Clinical Research

Yazarlar: Inudi Anupama, P.Vineela, P.Vineela, Siddula Shireesha

Konular:-

Anahtar Kelimeler:Sublingual Misoprostol,Intramuscular Oxytocin,Haemoglobin.

Özet: Aims: This study was done to assess the efficacy of oral misoprostol in the active management of the 3rd stage of labour in comparison with intramuscular oxytocin and to assess the side effects of the drugs. Materials and methods: 200 women of low risk category were selected randomly with 100 women in each group. After delivery of the baby, the cord was clamped and cut. Misoprostol group was given 3 tablets of misoprostol 200μg each sublingually and oxytocin group was given 10 IU of oxytocin in the intramuscularly. Placenta was delivered by controlled cord traction. Blood loss was measured in both the groups for 1st hour after delivery. The hemoglobin concentration before and 24 hours after delivery was noted. The side effects of the drugs up to 24 hours after delivery were noted. Results: The results of the misoprostol group (100 patients) were compared with oxytocin group (100 patients). The average blood loss was 217.9 ml in misoprostol group compared to 233.45 ml in oxytocin group. The fall in hemoglobin percentage was 0.9g/dl in misoprostol group compared to 0.8g/dL in oxytocin group. The difference in observation of both groups was statistically not significant (p>0.05). The incidence of postpartum hemorrhage was 2% in both the groups. There was no case of retained placenta in either of the groups. The need for additional oxytocics was also 2% in both the groups as they were given only when the blood loss is more than 500 ml. Shivering and pyrexia were the commonest side effects noted in misoprostol group. Conclusion: We found that both sublingual misoprostol and intramuscular oxytocin were equally effective in the management of 3rd stage of labour.

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