International Journal of Health and Clinical Research

Yazarlar: Thomas Mathew, Sheela Jacob D

Konular:-

Anahtar Kelimeler:Guillian Barre Syndrome,Demyelinating diseases,Dysautonomia,Poluradiculoneuritis,Nerve conduction.

Özet: Background- Acute inflammatory polyradiculoneuritis, the Guillain-Barre’ Syndrome (GBS) has come to be accepted as a clinical entity, although the boundary between it and chronic inflammatory demyelinating polyneuropathy has given rise to discussion. Objectives-To study the various epidemiological, clinical features of patients admitted with Guillain-Barre’ Syndrome and complications in these patients. Methods-All adult patients, diagnosed as Guillain-Barre’ Syndrome, who strictly complied with the NINCDS criteria, admitted to Christian Medical College and Hospital, Ludhiana from 1st July 1988 to June 30th 1993 were included in this study. This includes a retrospective study of four years and prospective study of one year. Ninety seven patients entered the study. SPSS(Version 22.0) was used for analysis. Results-the incidence of GBS was more in the younger group. 70% of our cases were below 40 years of age. 80.34% were males and 19.65% were females.The agriculturists formed the maximum number of patients (32%) under study followed by students (22%) and house wives (16%).upper respiratory tract infection was present in the maximum number of patients (72.8%).dysautonomia was seen in 54.6% of patients. Twenty one patients (21.6%) received prednisolone and 4 (19%) of the groupexpired. 76 patients (78.2%) did not receive prednisolone and 21 (27.6%) patients expired in this group. Conclusion-There was no significant difference in the outcome of patients who received and who did not receive prednisolone as the treatment modality.

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