Asian Pacific Journal of Health Sciences

Yazarlar: M Mitra, N C Nanda, SS Bhattacharya, M Dasgupta

Konular:-

DOI:10.21276/apjhs.2018.5.3.3

Anahtar Kelimeler:Ampicillin,Antibiotic Resistance,Drug Vacation,Neonate

Özet: Objectives: To compare the antimicrobial sensitivity patterns in neonatal infections in the year 2011 and 2014 in a Tertiary care Hospital in east India. Methodology: A retrospective study was done by collecting data from medical records of 150 neonates with positive cultures for blood, urine and cerebrospinal fluid in a Tertiary care hospital of Rourkela, Odisha. The antibiotic sensitivity patterns of the years 2011 and 2014 were tabulated. The data was analyzed using chi square test. Results: A statistically significant decrease in resistance to Ampicillin was seen in 2014 when compared to 2011 (p value=0.011) Conclusion: The advent of higher antibiotics has led to decreased use of baseline antibiotics like Ampicillin. The subsequent "drug vacation" may have led to the lower Ampicillin resistance.

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