Asian Pacific Journal of Health Sciences

Yazarlar: Nupur Rastogi

Konular:-

DOI:10.21276/apjhs.2019.6.1.16

Anahtar Kelimeler:Epithelioid,Leiomyosarocma,Uterus

Özet: Fibroid most commonly presents in the reproductive age group. Leiomyosarcoma of uterus occurs in 1-2 %of uterine sarcoma. Epithelioid Leiomyosarcoma of myometrium is rare malignant tumor that arises from the smooth muscle lining the walls of the uterus. A 45 year old female presented with abnormal uterine bleeding, Ultrasonography showed a fibroid measuring 5x5 cm in body of uterus. Hysterectomy revealed a polypoidal growth in endometrial canal with haemorrhage and necrosis. H & E sections revealed histological features of epithelioid Leiomyosarcoma of uterine wall. IHC confirmed the diagnosis with SMA, ER, PR, Ki-67 markers being positive. Prognosis of this tumor is poor with 5 year survival rate depending on the size and stage of the tumor at presentation. Hence, accurate histopathological diagnosis confirmed on IHC is essential.

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