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Records of Natural Products
Yazarlar: Fei Li, Liang Ma, Jinyuan Zhang, Xueling Qiao, Dingshan Zhang, Dongbo Zhang
Konular:-
DOI:10.25135/rnp.233.21.02.1968
Anahtar Kelimeler:Jatropha multifida,Tirucallane triterpene,Anti-inflammatory activity,Thioredoxin reductase
Özet: Jatroidaine A (1), a new tetranortirucallane-type triterpene, and two known analogues (2−3) were isolated from the leaves and branches of Jatropha multifida. Their structures were fully elucidated by extensive spectroscopic methods and comparison to known compounds. The absolute configuration of 1 was assigned by single-crystal X-ray diffraction analysis. All compounds were evaluated for their anti-inflammatory and thioredoxin reductase (TrxR) inhibitory activities. Unfortunately, no significant activity was observed.