Records of Natural Products

Records of Natural Products

1 Bioactive Natural Products from Endophytic Fungus Aspergillus nidulans Associated with Nyctanthes arbor-tristis Linn.

Yazarlar: Talea Sana, Bina Siddiqui, Majid Khan, Saleem Shahzad, Samia Sattar, Sabira Begum

Cilt 15 , Sayı 6 , 2021 , Sayfalar 608-612

Konular:-

DOI:10.25135/rnp.251.21.02.1986

Anahtar Kelimeler:Aspergillus nidulans;,Nyctanthes arbor-tristis;,Xanthone

Özet: Endophytic fungi are a substantial source of bioactive secondary metabolites. Present studies on Aspergillus nidulans―an endophytic fungus from Nyctanthes arbor-tristis Linn. afforded one new 1, 5-dihydroxy-3-methylxanthone-6-carboxylic acid methyl ester (1) and one known 5, 10-dihydro-phenazine-1-carboxylic acid (2) compound. The structures were elucidated by spectral techniques (Mass, 1D and 2D NMR), and their urease, carbonic anhydrase and prolyl endopeptidase inhibitory activities were evaluated. Compound 1 showed notable prolyl endopeptidase inhibition (IC50 = 3.13 ± 0.09 µM) and compound 2 showed significant carbonic anhydrase (IC50 =14.3 ± 1.05 µM) and urease (IC50 = 24.3 ± 1.15 µM) inhibition.

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@article{2021, title={1 Bioactive Natural Products from Endophytic Fungus Aspergillus nidulans Associated with Nyctanthes arbor-tristis Linn.}, volume={15}, number={608–612}, publisher={Records of Natural Products}, author={Talea Sana, Bina Siddiqui, Majid Khan, Saleem Shahzad, Samia Sattar, Sabira Begum}, year={2021} }
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Talea Sana, Bina Siddiqui, Majid Khan, Saleem Shahzad, Samia Sattar, Sabira Begum. (2021). 1 Bioactive Natural Products from Endophytic Fungus Aspergillus nidulans Associated with Nyctanthes arbor-tristis Linn. (Vol. 15). Vol. 15. Records of Natural Products.
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Talea Sana, Bina Siddiqui, Majid Khan, Saleem Shahzad, Samia Sattar, Sabira Begum. 1 Bioactive Natural Products from Endophytic Fungus Aspergillus Nidulans Associated with Nyctanthes Arbor-Tristis Linn. no. 608–612, Records of Natural Products, 2021.
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